Tribedoce: Functions/Dosage/Uses/Side Effects & Precautions

Tribedoce: Functions/Dosage/Uses/Side Effects & Precautions

Have you been recommended tribedoce as a treatment for your vitamin B12 deficiency and you want to learn more about it?

Then you have come to the right place, as this article covers all the information you require about Tribedoce, including how it functions, the suggested dosage, uses, side effects, and precautions you need to take when taking this medication.

Tribedoce is a medication that doctors recommend to patients who are B12 deficient. It serves as a supplement.

Although only in small amount is required by the body, vitamin B12, also known as cyanocobalamin, is needed for DNA synthesis and maintenance of healthy nerve and blood cells as well as brain and nerve growth.

Megaloblastic anemia, a blood disorder that causes fatigue and weakness, is another ailment that vitamin B12 helps to prevent.

What if your body lacks this essential vitamin, perhaps as a result of conditions like anemia or from regularly consuming meals low in vitamin B12?

In such a case, you might start looking for supplements to help you increase this vitamin in your diet.

What is Tribedoce?

A synthetic form of vitamin B12 (Cyanocobalamin) is used to treat and prevent vitamin B12 insufficiency.

We get vitamin B12 through the foods we eat, such as cattle, liver, chicken, fish, and clams, among other shellfish. B12 is also present in cereals, milk, yogurt, cheese, and eggs.

Tribedoce, a supplement, is used to make up for this vitamin B12 deficiency as well as various other vitamins, including pyridoxine hydrochloride and thiamine hydrochloride (Vitamin B1).

Tridoce contains these two additional vitamins as well.

Tribedoce Functions Dosage Uses Side Effects Precautions
Tribedoce Functions Dosage Uses Side Effects Precautions

How does Tribedoce work?

Tribedoce is a dietary supplement that contains several water-soluble vitamins, including Vitamin B1-Thiamine Hydrochloride, Vitamin B12-Hydroxocobalamin, and Vitamin B6-Pyridoxine Hydrochloride

It has a high level of biological activity.

Tribedoce functions via taking part in transmethylation, hydrogen transport, and the production of methionine, nucleic acid, choline, and creatine.

It promotes the accumulation of sulfhydryl-containing compounds in erythrocytes and the neurological system and the liver both perform better as a result.

It increases blood clotting and boosts thromboplastin and prothrombin activity.

All of these actions aid in the production of red blood cells and the growth of the brain and nerves.

It comes in the following different forms;

  • Subcutaneous Injections (SC).
  • Intravenous Injections (IV).
  • Intramuscular Injections (IM).
  • Intra-lumbar Injections (IL).
  • Oral form.

To know how to use this medication properly, you must be aware of the prescribed dosage recommendation;


  • Tablet form: The recommended dosage is one tablet taken three times daily, or as prescribed by a doctor. It is advised to take 1 tab each day when pregnant.
  • Injections: In dire cases, 1 amp daily by IM injection, if possible by gradually intragluteal, till the acute symptoms fade.

1 amp 2-3 times weekly for milder cases and a follow-up therapy because of the probability of sensitivity to vitamin B1, Tribedoce IV, IL, and SC injections should be done slowly and gently, ideally as an infusion.

Information on Dosage

  • For issues with the neurological system, take 200–400 mcg 2-4 times per month.
  • 30-100 mcg 2-3 times a week for acute posthemorrhagic anemia and iron anemia.
  • For aplastic anemia (especially in children): 100 micrograms before clinical improvement.
  • For newborns and preterms with nutritional anemia, take 30 mcg each day for 15 days.
  • Amyotrophic lateral sclerosis may be injected into the spinal canal with a dosage of 15 to 30 micrograms for funicular myeloid disease, rising over time to 200 to 250 micrograms.
  • Medication is used in ascending doses ranging from 200 to 500 mcg for neurological diseases with a pain syndrome, as well as illnesses of the central and peripheral nervous systems. When you start to feel better, up the dosage to 100 mcg each day.
  • For Anemia deficiency: 100-200 mcg in 2 days.
  • For cirrhosis and hepatitis: 30-60 mcg/day or 100 mg every other day for 25-40 days.
  • For funicular myeloid anemia and melanocytic anemia with nervous system illnesses: 400-500 micrograms daily for the first 7 days/1 week, then 1 time every 5-7 days. In the absence of funicular myeloid episodes, the maintenance dosage is 100 mcg twice a month during the remission phase.
  • For Traumatic peripheral nerve system lesions: 200-400 mcg every other day for 40-45 days.
  • For radiation sickness, diabetic neuropathy, and sprue: 60-100 mcg every day for 20-30 days.
  • For dystrophy in young children, down syndrome, and cerebral palsy: 15-30 mcg every other day.

What happens if Tribedoce dose(s) are missed?

If you missed/forgot to take your Tribedoce dose, do the following:

Take your next dose at the normal time and in the normal amount. Never take more than your doctor prescribed.

Skip the missed dose and carry on with your normal schedule. Contact your doctor for instructions if you miss a dose.

Before you run out of medicine, have your prescription filled?

What happens if you overdosed on Tribedoce?

Even high doses of B12 do not pose a health risk since any excess will be removed through your urine because it is water-soluble.

However, you should call your healthcare provider or see your doctor right away if you experience any severe symptoms or side effects.

Tribedoce Functions Dosage Uses Side Effects Precautions
Tribedoce Functions Dosage Uses Side Effects Precautions

The effects of Tribedoce may change if you also use other drugs, substances, or herbal remedies at the same time

You could be at risk for serious side effects or the medicine could stop working effectively as a result.

This medication interaction is possible, though not usually present.

Your doctor or pharmacist can usually prevent or control interactions by changing the way you take your medications or by constantly monitoring you.

Tribedoce and the following medicines may interact negatively, thereby raising the possibility of adverse effects;

  • Aspirin
  • Metformin
  • Stavudine
  • Loop Diuretics.
  • Tricyclic
  • Thiamine
  • Anti-depressants
  • Vitamin B1 or any constituent of a vitamin B1-containing product.
  • Vitamins/supplements that contain intrinsic factors.
  • Drugs that affect the bone marrow like chloramphenicol.

Tribedoce can interact negatively with the following medicines to lessen their effects on your body;

  • Heartburn medications
  • Colchicine
  • Metformin
  • Antibiotics
  • Vitamin C
  • Bile acid sequestrants to lower cholesterol
  • Extended-release potassium products
  • Anti-seizure medications

The following disorders or allergies may interact with Tribedoce which include;

  • Kidney illness
  • A rare blood disorder called Polycythemia vera.
  • Allergy to cyanocobalamin or cobalt
  • Low potassium levels – Hypokalemia.
  • Deficiencies in other nutrients, mainly folic acid, and iron.
  • A hereditary form of vision loss is called Leber’s disease.

To help them give you the best care possible, be sure to tell your doctor and pharmacist about everything you take (including prescription medications, over-the-counter medicines, other substances, and herbal products) before starting treatment with this product.

While using this product, do not begin, stop, or change the dosage of any other medications you are taking without first consulting your doctor.

Benefits of Tribedoce in the body

The following are some potential advantages of the Tribedoce shot, according to Healthline;

Enhanced Cognitive Function

The loss of brain function has been connected to low levels of Tribedoce (vitamin B12). There may be a connection between low blood levels and dementia development, according to two recent assessments.

There have been conflicting findings, and vitamin B12 therapy did not enhance brain function in those with normal brain function.

Help With Depression

Depression and low vitamin B12 levels have been linked, it has been suggested.

A review discovered that using vitamin B12 to treat depression did not lessen the intensity of symptoms.

Nevertheless, it was proposed that long-term vitamin use might aid in preventing depression relapse. There isn’t enough good research being done in this field right now.

To determine whether there is a connection between and depression, higher quality studies are required.

Reduced Osteoporosis Risk

Osteoporosis is a condition in which a person’s bones get weaker and are more prone to breaking.

It’s interesting to note that lower bone mass has been associated with lower blood levels of vitamin B12.

Tribedoce has so been recommended as a possible way to lower your chance of developing osteoporosis. Studies, though, have produced a range of outcomes.

Macular Degeneration Caused by Age

A disorder called age-related macular degeneration causes you to gradually lose your central vision, typically in both eyes.

It is believed that getting enough vitamin B12 is crucial for adults over 50 to keep their vision healthy and prevent macular degeneration.

What is the potential side effect of Tribedoce shots?

Tribedoce has no upper consumption limit because there is no chance of toxicity or overdose.

Tribedoce injections could also cause other negative effects.

A doctor should be consulted if any minor side effects or potential dangers develop or persist. These include:

  • Pain, swelling, or itchiness where the injection was made.
  • Minimal diarrheal illness
  • A feeling of swelling throughout the body

Serious adverse effects that necessitate prompt medical treatment include:

  • spasms in the muscles
  • An irregular pulse
  • Unusual weariness or a weakness
  • enlargement of the ankles or feet

Severe reactions are very rare but require emergency intervention

These consist of:

  • Facial, throat, or tongue edema in addition to itchiness
  • having trouble breathing
  • severe lightheadedness
  • abrupt shifts in vision
  • speech that is slurred

Remember that if your doctor has recommended this medication, it is because they believe you will benefit from it more than the risk of side effects.

Many users of this medication report no significant side effects. To get the maximum benefit from this medication, take it exactly as directed.

Precautionary Measures for Taking Tribedoce

Tribedoce passes into breast milk when provided at the recommended doses, therefore it is unlikely to harm a nursing infant. If you plan to breastfeed, talk to your doctor.

Alcohol consumption while taking drugs as directed by a pharmacist is risky since it makes patients drowsy and jeopardizes their health.

If you are allergic to cobalt, any type of vitamin B12, cyanocobalamin, or any other vitamin, be sure to let your doctor or pharmacist know.

This product’s inactive ingredients could result in issues like allergic reactions. Consult your pharmacist for more details.

Before taking this medication, talk to your doctor or pharmacist if you have Leber’s disease, gout, iron- or folic-acid-deficiency anemia, low potassium levels in the blood (hypokalemia), or any of the other conditions listed below.

To receive all the benefits and prevent any potential side effects, it is essential to take the right dose at the right time.

Tell your doctor if you are expecting or nursing a child. Your dosage needs may change if you’re breastfeeding or pregnant.

Is Tribedoce safe to take, especially over the long term?

Tribedoce is water-soluble, so even huge doses will not be dangerous to your health.

Any excess will be expelled through your urine, and the duration will be decided by your doctor specifically for your condition.

Consider it risky to drive or operate heavy machinery after taking Tribedoce if you feel weak, drowsy, or dizzy as a result of it.

That is to say, if you experience any odd side effects like fatigue or dizziness after taking the medication, avoid operating heavy machinery or driving.

Alcohol consumption while taking drugs as directed by a pharmacist is risky since it makes patients drowsy and jeopardizes their health.

It’s important to call your doctor on time for the right advice and medical consultations.

To receive all the benefits and prevent any potential side effects, it is essential to take the right dose at the right time.

How long do you have Tribedoce before you see improvements?

The course of treatment with Tribedoce (Vitamin B12 (Hydroxocobalamin)) last for two weeks before you begin to see results, but that doesn’t indicate the supplement wasn’t effective up until that point.

It began functioning the moment you began taking the drug, but it will take two weeks before any palpable improvements are visible.

Depending on your health, your doctor may occasionally recommend the drug for a month or even a lifetime.

Causes of Vitamin B12 Deficiency

The following individuals frequently lack enough vitamin B12. See the causes;

  • Individuals with specific medical conditions: Those who have undergone intestinal surgery, including weight loss surgery, are also susceptible to deficiency. In addition, vulnerable folks with digestive conditions like Crohn’s or celiac disease.
  • The elderly: Deficiency is more prevalent in the elderly because the capacity to absorb vitamin B12 declines with age.
  • Vegetarians: Deficiency is frequent, especially in vegetarian and vegan diets. Up to 90% of those who consume these diets are thought to be inadequate. This is because B12 is only naturally present in animal diets.
  • Those who are lacking, however, are not just vegans and deficient. Even some meat eaters have trouble assimilating it. In contrast to other vitamins, vitamin B12 absorption is reliant on an intrinsic factor, a protein made in your stomach.
Signs that will alert you when your B12 levels are low

How may your natural vitamin B12 intake be increased or boosted?

Eat more foods that contain vitamin B12 to naturally boost your intake, such as:

  • Chicken
  • Fish and shellfish including salmon, tuna, mussels, and trout.
  • Beef
  • Liver
  • Yogurt
  • Cheese
  • Low-fat dairy
  • Fortified breakfast cereal.
How do you get your Vitamin B12 levels checked?

Taking a Vitamin B12 Test

A blood sample is needed for vitamin B12 testing, which is often collected from your arm in a doctor’s office, health center, hospital, or lab.

You will get the tools you need to draw your blood sample if you select an at-home kit that checks for vitamin B12.

Through a urine or hair sample, several micronutrient at-home tests may screen for B12 and other vitamins.

Before the test

You must refrain from eating or drinking anything other than water for six to eight hours before obtaining a vitamin B12 test.

Ask your doctor whether you need to temporarily stop taking any of your regular drugs because some of them can impact the outcomes of the vitamin B12 test.

During the testing

A little blood sample is often drawn from a vein in your arm during a vitamin B12 test performed at a lab or medical facility.

To make it simpler to see your veins, the medical professional taking your blood sample could wrap a band around your upper arm.

The spot where the needle entered your skin will next be cleaned. Your vein will be punctured with a needle connected to a sample tube, and a little amount of blood will be collected into the tube.

When the needle punctures your skin, you can experience a mild sting. A blood sample is often taken in less time than a minute.

After the test

You might be instructed to use a piece of cotton, gauze, or bandage to gently push down on the area where the blood was drawn.

After that, the area where the blood was drawn is bandaged. Providing a blood sample is an extremely low-risk procedure.

You could occasionally get a little bruise where the blood sample was obtained. If not, you can resume your regular activities.

How Soon Will I Start Feeling Better After Taking Tribedoce?

Treatment with tribedoce, a kind of vitamin B12 (hydroxocobalamin), typically lasts two weeks.

Consult your doctor, preferably the one who provided the prescription if you haven’t noticed any improvements by then.

Where can you buy Tribedoce?

This drug is available at your neighborhood pharmacy, hospital, and online retailers like Amazon.

What is the price of Tribedoce? How much does Tribedoce cost?

Depending on where you buy the supplement, what type or dosage you buy, and how much you buy, the drug might cost anywhere from $5 to $30.

The price of the medicine is determined by variables for example; the of the drug purchased, how effective it was for the money spent, the country or area where the drug is sold, and the patient’s financial status.

Users who think the medication is too expensive should look for a generic version or an alternative brand to save money.

Misconceptions to be cleared about Tribedoce

You need to dispel several myths about Tribedoce if you want to learn more about it;

Consuming too much tribedoce may be harmful: people need 2.4 micrograms of vitamin B12 daily while pregnant, and nursing mothers need 2.8 micrograms daily.

Being a water-soluble vitamin, your body eliminates any extra amounts through urine. In other words, it is typically viewed as safe even at high dosages.

There is no Tolerable Upper Intake Level (UL) for vitamin B12 due to its low toxicity, therefore you don’t need to be concerned about taking too much through food or supplements.

Tribedoce treats heart disease and stroke: Higher homocysteine levels may be associated with a higher risk of having a heart attack or a stroke. Only those with a confirmed B12 deficiency can take tribedoce, which may lower homocysteine levels and lessen their chance of developing heart disease.

Tribedoce is only for vegetarians since they are very commonly vitamin B12 deficient: Due to vitamin B12’s availability in animal products, many people mistakenly think that vitamin B12 deficiency only affects vegans and vegetarians.

However, anyone could be at risk for vitamin B12 deficiency as lifestyles, diets, and medications change.

You are more likely to experience vitamin B12 deficiency, for instance, if you take specific medications to treat heartburn or lower stomach acid or if you adhere to a strict diet.

Additionally, having gastrointestinal issues, being over 50, or having undergone gastric bypass surgery increases your risk of vitamin deficiency.

Frequently Asked Questions about Tribedoce

What are the different forms that tribedoce is available in?

Tribedoce is a medication that can be administered orally and subcutaneously (SC), intravenously (IV), intramuscularly (IM), and intralumbarly (IL).

How frequently should I take B12 tablets?

You could be instructed to take vitamin B12 supplements every day in between meals if your vitamin B12 shortage is due to a deficiency in your diet.

Alternatively, you might require a hydroxocobalamin injection twice a year.

When is the best time to take B12 morning or night?

You can either get a variety of B vitamins from a multivitamin or a particular kind from a single vitamin.

As a general rule of thumb, take your B vitamins in the morning or with a meal, advise health professionals at Click Pharmacy.

For instance, vitamin B12 must unquestionably be taken in the morning.

How long do the side effects of Tribedoce last?

The adverse effects often disappear after a week, but if you are having particularly severe side effects or if they don’t go away, call your doctor immediately once.

Can you drive or operate heavy equipment after using Tribedoce?

After using Tribedoce, you should not drive or operate heavy machinery if you feel weak, drowsy, or dizzy depending on how your body reacts to the medication.

In other words, if you feel strange side effects like fatigue or dizziness after taking the medication, do not drive or operate heavy machinery.

According to a pharmacist, it is dangerous to drink alcohol while taking drugs since it can make patients sleepy and put their health at risk.

Please remember this, especially if you take Primosa capsules. To receive appropriate information and medical consultations, it is imperative to call your doctor as soon as possible.

Is Tribedoce addictive or habit-forming?

Not at all, no. Medicines are not intended to lead to drug addiction or health misuse.

Addictive drugs are classified as controlled substances by the government.

Schedule H or X in India and Schedule II-V in the US are two examples of controlled substances.

Before using a medication, please check the medication’s instruction manual to make sure it is not a prohibited substance. In conclusion, self-medication is bad for your health.

Before taking any drug, speak with your doctor to get an appropriate prescription, suggestions, and instructions.

Does Tribedoce have ant withdrawal side effects or symptoms?

Nope. It wasn’t intended to be that way. It does not have withdrawal symptoms because it is not a mood-stimulating drug.

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